There are a number of different options that can be chosen when running VTune. A full list of available options can be found here. I have gone through the list and picked out ones that I think could be useful:
-target-duration-type: Adjust the sampling interval for longer-running targets.
-target-duration-type=medium is important for longer runs (>15 minutes) as VTune will stop collecting data after 500MB by default so you may only obtain a profile of the first half of your simualtion. Can be used in conjunction with -data-limit=0 to set no limit of the total amount of data collected.
-data-limit: Limit the amount of raw data (in MB) to be collected.
-ring-buffer: Limit the amount of raw data to be collected by setting the timer that enables the analysis only for the last seconds before the target or collection is terminated.
-search-dir: Specify a search directory for binary and symbol files.
-inline-mode: Exclude/include inline functions in the stack. -inline-mode=off is useful if you want to remove false-positives from the profile, which makes the time of inline functions appear in the total time of the parent function instead of appearing as a separate function in the profile.